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In this case take the smaller dose in the morning and the higher dose before you go to bed. The usual starting dose for mirtazapine is 15 to 30mg a day. If you have problems with your liver or kidneys your doctor might prescribe a lower dose.

If you take mirtazapine once a day and miss a dose, skip it and take the next dose at the normal time.

It recommended generic SSRIs as first line choices, as they are "equally effective as other antidepressants and have a favourable risk–benefit ratio." With respect to mirtazapine, it found: "There is no difference between mirtazapine and other antidepressants on any efficacy measure, although in terms of achieving remission mirtazapine appears to have a statistical though not clinical advantage.Do not take a double dose to make up for a forgotten dose.If you take mirtazapine twice a day and forget: If you forget doses often, it may help to set an alarm to remind you.receptor tends to desensitize and the antihistamine effects become more tolerable.Many patients may also dose at night to avoid the effects, and this appears to be an effective strategy for combating them.

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